The study investigates the development of cortical interneurons, particularly focusing on GABAergic neurons in the early postnatal period of mice. These neurons play a crucial role in integrating sensory experiences, yet their dynamics during this stage were not well understood. Using in vivo calcium imaging, the research reveals a transient organization in GABAergic population activity,…

Zhe Ran S Duan, Alicia Che, Philip Chu, Laura Modol, Yannick Bollmann, Rachel Babij, Robert N Fetcho, Takumi Otsuka, Marc V Fuccillo, Conor Liston, David J Pisapia, Rosa Cossart, Natalia V De Marco García DOI: 10.1016/j.neuron.2019.10.008 Abstract During neonatal development, sensory cortices generate spontaneous activity patterns shaped by both sensory experience and intrinsic influences. How these patterns contribute to the assembly of neuronal circuits is not clearly understood.…